"Is it painful?" It’s the most commonly asked question of bone marrow donors, and it’s often asked rhetorically, because people believe they know the answer. In fact, most people believe that bone marrow donation is about as painful as childbirth or passing a kidney stone. But, while bone marrow donation isn't completely painless (you wake up feeling as if you just took a spill on the ice), it's nearly so. Doctors now harvest bone marrow while patients are under general anesthesia, so you don't feel a thing until you're already in recovery. Here are the five other common myths about bone marrow donation which is one of the most fascinating, but misunderstood, life-saving missions.